Peyronie's Disease was first described in 1743 by a French surgeon, Francois de la Peyronie and was written about as early as 1687. The disease is oftentimes associate
The most common symptom of Peyronie's Disease is a curvature, lump or hard area observed in the penis. Painful erections and penile pain are also symptoms of this condition. . The lumps or hard areas, also referred to as plaque or scar tissue form between the tunica and the outer layers of skin. The plaque or scarring also reduces the elasticity to the affected area, it will not stretch as the surrounding, unaffected tissues. The erect penis bends in the direction of the scar or plaque formation as a result of this, often with associated pain.
Recent studies in Europe report three percent of men have Peyronie's Disease. Statistics gathered show the average age of the patient to be 55, although patients as young as 16 and as old as 83 have been treated. About 30 percent of the patients with Peyronie's Disease also develop fibrosis in other tissues of the body, such as the hands and feet. This group of patients with involvement in more than one body part may have been born with a genetic predisposition to the disease. This genetic predisposition can occur in women as well.
Many physicians believe that the plaque associated with Peyronie's Disease develops as a result of trauma to the penis that causes localized bleeding inside the penis. Repeated trauma to the damaged area may prevent normal healing, or very slowl healing. As the plaque that forms hardens, it becomes fibrotic and sometimes allows for calcium deposits.
For more information on other diseases that can be treated with Topical Verapamil, follow the links for each disease.
Keloids are raised, reddish nodules that develop at the site of an injury. After a wound has occurred to the skin both skin cells and connective tissue cells (fibroblasts) begin multiplying to repair the damage.
Ledderhose Disease Disorder of unknown etiology characterised by local proliferation of abnormal fibrous tissue in the plantar fascia. This tissue is locally aggressive and progressively replaces the normal plantar aponeurosis.
Peyronie's Disease is a curvature, lump or hard area observed in the penis. Painful erections and penile pain are also symptoms of this condition.
Trigger Finger is caused by a thickening on the tendon catching as it runs in and out of the sheath. The most common cause is tenosynovitis.
Dupuytren's Contracture is a thickening of deep tissue (fascia) which passes from the palm into the fingers. Shortening of this tissue causes "bands" which pull the fingers into the palm.
Frozen Shoulder is shoulder joint that is significantly limited in its range of motion in all directions. The range of motion is limited not only when the patient attempts motion, but also when the doctor attempts to move the joint fully while the patient relaxes.
Hypertrophic Scar looks similar to a keloid. Hypertrophic scars are more common. They don't get a big as keloids, and may fade with time. They occur in all racial groups.
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